Does diabetes protect against developing MND?

The role of pre-morbid diabetes on developing amyotrophic lateral sclerosis. D’Ovidio F, d’Errico A, Carnà P, Calvo A, Costa G, Chiò A. Eur J Neurol 2017; doi: 10.1111/ene.13465. (Epub ahead of print). Abstract BACKGROUND AND PURPOSE: The literature on the association between diabetes and amyotrophic lateral sclerosis (ALS) consists of a limited number of studies.… Read More Does diabetes protect against developing MND?

Does prior chemotherapy protect against developing MND?

Medical history of chemotherapy or immunosuppressive drug treatment and risk of amyotrophic lateral sclerosis (ALS) Kuczmarski T, Stommel EW, Riley K, et al. J Neurol 2017; 264:1763-1767. Abstract Background A recent population-based analysis demonstrated lower risk of the lethal degenerative neuromuscular disease, amyotrophic lateral sclerosis(ALS) associated with history of the use of ‘antineoplastic agents‘ and ‘immunosuppressants’. Methods To see if this… Read More Does prior chemotherapy protect against developing MND?

Does marriage improve survival in people with MND?

Marital status is a prognostic factor in amyotrophic lateral sclerosis Spataro R, Volanti P, Lo Coco D, La Bella V. Acta Neurol Scand 2017; doi: 10.1111/ane.12771 (Epub ahead of print). Abstract Background: Several variables have been linked to a shorter survival in patients with amyotrophic lateral sclerosis(ALS), for example, female sex, older age, site of disease… Read More Does marriage improve survival in people with MND?

Is farming a risk factor for motor neurone disease?

Farming and incidence of motor neuron disease: French nationwide study Kab S, Moisan F, Elbaz A Eur J Neurol 2017 (Epub ahead of print). Abstract BACKGROUND AND PURPOSE: The association of farming with motor neuron disease (MND) is unclear, with conflicting studies. We performed a French nationwide study of the association of farming with MND… Read More Is farming a risk factor for motor neurone disease?

Will edaravone improve the outcome of motor neurone disease?

Clinical efficacy of edaravone for the treatment of amyotrophic lateral sclerosis Sawada H Expert Opin Pharmacother 2017; 18:735-738. Abstract Introduction: Amyotrophic lateral sclerosis (ALS) is a progressive, fatal, neurodegenerative disease. Although the pathogenesis remains unresolved, oxidative stress is known to play a pivotal role. Edaravone works in the central nervous system as a potent scavenger… Read More Will edaravone improve the outcome of motor neurone disease?

What is the benefit of meditation training in MND?

Meditation training for people with amyotrophic lateral sclerosis: a randomized clinical trial. Pagnini F, Marconi A, Tagliaferri A, et al. Eur J Neurol 2017; 24:578-586. ABSTRACT Background: Studies investigating psychological interventions for the promotion of well-being in people with amyotrophic lateral sclerosis (ALS) are lacking. The purpose of the current study was to examine the… Read More What is the benefit of meditation training in MND?

Is motor neurone disease in HIV a treatable disorder?

 HIV-associated motor neuron disease. HERV-K activation and response to antiretroviral therapy Bowen LN, Tyagi R, Li W, et al. Neurology 2016; 87:1756-1762. Abstract OBJECTIVE: To determine whether there is activation of human endogenous retrovirus K (HERV-K) in amyotrophic lateral sclerosis in HIV infection and whether it might respond to treatment with antiretroviral drugs. METHODS: In… Read More Is motor neurone disease in HIV a treatable disorder?