Management of adults with acute migraine in the emergency department: The American Headache Society Evidence Assessment of Parenteral Pharmacotherapies. Orr SL, Friedman BW, Christie S, et al. Headache 2016; 56:911-940. Abstract OBJECTIVE: To provide evidence-based treatment recommendations for adults with acute migraine who require treatment with injectable medication in an emergency department (ED). We addressed… Read More What is the recommended emergency room treatment of migraine?
Neurologists are often slightly nervous when their patients start planning a family. It’s even worse when the patients fall pregnant–unexpectedly. This is because neurologists need super thinking hats not only to anticipate the potential impact of pregnancy on their patients neurology, but also to preempt the adverse effects of neurological treatments on the developing baby. The nervousness… Read More What are the most important neurological conundrums of pregnancy?
Pregnancy outcome after anti-migraine triptan use: a prospective observational cohort study Spielmann K, Kayser A, Beck E, Meister R, Schaefer C Cephalalgia 2017; 1:333102417724152 Abstract Objective The objective of our study is to assess the impact of triptan exposure on pregnancy outcome. Methods We performed a prospective observational cohort study with 432 pregnant women… Read More Are triptans safe for treatment of migraine in pregnancy?
Distinguishing characteristics of headache in nontraumatic subarachnoid hemorrhage Mac Grory B, Vu L, Cutting S, Marcolini E, Gottschalk C, Greer D. Headache 2018; 58:364-370. Abstract INTRODUCTION: Subarachnoid hemorrhage (SAH) is a life-threatening emergency that is frequently missed due to its varied and often subtle presentation. The most common presentation of SAH is with a severe… Read More What are the distinctive features of headache in subarachnoid haemorrhage?
Dural venous sinus stenting for medically and surgically refractory idiopathic intracranial hypertension Satti SR, Leishangthem L, Spiotta A, Chaudry MI. Interv Neuroradiol 2017; 23:186-193. Abstract Background: Idiopathic intracranial hypertension (IIH) is a syndrome defined by elevated intracranial hypertension without radiographic evidence of a mass lesion in the brain. Dural venous sinus stenosis has been increasingly… Read More What is the benefit of dural venous sinus stenting for IIH?
Serotonin receptor targeted therapy for migraine treatment: an overview of drugs in phase I and II clinical development Barbanti P, Aurilia C, Egeo G, Fofi L, Palmirotta R. Expert Opin Investig Drugs 2017; 26:269-277. Abstract Background: Research has focused on serotonin (5-HT) 5-HT1D and 5-HT1F receptors to develop drugs acting through non-vasoconstrictive mechanisms for treating acute migraine… Read More Is lasmiditan the next big thing in the fight against migraine?
Headaches constitute the bulk of what neurologists see in their general clinics. Most people with headaches fall neatly into one of two categories, migraine or tension type headache (TTH). The neurology clinic may have a sprinkling of people with cluster headache or paroxysmal hemicrania, two of the more common trigeminal autonomic cephalalgias (TACs). All these headaches are easy to recognise… Read More The most unusual headache syndromes in neurology