What are the most important neurological questions of 2020?

It is the season again for reflecting over the most important neurology papers published in the year. Because we keep a keen eye on the relevant journals and neurology headlines, we are well-placed at Neurochecklists to pinpoint those papers which asked the most pressing neurological questions, and either answered them, or pointed to where the wind is blowing.

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Over the course of 2020 we publicised more than 70 papers which have greatly improved our understanding of nervous system disorders. Some of these papers received only a tepid reception by the almost 14,000 visitors to our blog post this year. Other studies were however attention-grabbers, helping us to mark up almost 23,000 views this year.

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So which are the studies that rose to the occasion and asked the tricky questions that bedevil neurology? To answer this, we analysed which papers had the most views this year, and came up with 20 most important neurological questions of 2020. Here is the countdown:

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How does body weight influence the risk of MND?
How effective is rituximab in refractory myasthenia gravis?
What is the picture of Guillain Barre syndrome in COVID-19?
Do seizures at stroke onset increase the risks of thrombolysis?
What are the characteristics of stroke in COVID-19?
What are the sleep-related disorders of multiple sclerosis?
Do vaccinations increase the risk of developing MS?
What are the characteristics of headache in COVID19?
What factors predispose to the psychiatric side effects of levetiracetam?
Which anti-MOG antibody treatment has the lowest relapse risk?
By Salazar210 at English Wikipedia, CC BY-SA 3.0, Link
Does IIH increase the risk of cerebrovascular events?
How much is the risk of SUDEP increased in those who sleep alone?
Is thrombolysis beneficial when time of stroke onset is unknown?
Is thrombolysis beneficial for central retinal artery occlusion?
How does CSF analysis distinguish neurosarcoidosis from multiple sclerosis?
Is thrombolysis effective in spinal stroke?
What features predict poor outcome following shunt surgery for NPH?
How do hand postures localise the site of seizure onset in epilepsy?
Is intravenous methylprednisolone effective in ocular myasthenia gravis?

And the most important question of 2020 was:

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How is the heart affected in transient global amnesia?


Because this blog is more than just questions and answers, you may also want to check out the following 10 posts that also made headlines in 2020:


For the full context…go to Neurochecklists.

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By Ibrahim Imam

I am a UK Neurologist keen on general neurology, but with an interest in neuromuscular diseases. I maintain the neurology searchable database, I also blog at I share and discuss current issues around clinical neurology. I hope you find my blogs enlightening, practical, and even entertaining.

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