Is migraine a risk for suicide?

Association of suicide risk with headache frequency among migraine patients with and without aura.

Lin YK, Liang CS, Lee JT, et al.

Front Neurol 2019; 10:228.

Abstract

Background:

Migraines with aura have been associated with suicide in adolescents and young adults, but the association between suicide and migraine frequency has not been determined. This study investigated suicidal ideation and suicide attempts among patients with varying frequencies of migraines, with and without auras.

Methods:

This cross-sectional study analyzed 528 patients aged between 20 and 60 years from a headache outpatient clinic in Taiwan. All patients completed a set of questionnaires, including a demographic questionnaire, the Migraine Disability Assessment questionnaire, the Hospital Anxiety and Depression Scale, the Beck Depression Inventory, and the Pittsburgh Sleep Quality Index. Suicide risk was evaluated by self-reported lifetime suicidal  ideation and attempts. Patients were divided into low-frequency (1-4 days/month), moderate-frequency (5-8 days/month), high-frequency (9-14 days/month), and chronic (≥15 days/month) migraine groups. The association between migraine frequency and suicidality was investigated using multivariable linear regression and logistic regression.

Results:

The rates of suicidal ideation and suicide attempts were the highest for chronic migraine with aura (ideation: 47.2%; attempts: 13.9%) and lowest in migraine-free controls (2.8%). Migraine frequency was an independent risk factor for suicidal ideation and attempts in patients with aura (both P trend < 0.001), but not in patients without aurasMigraine aura and depression were associated with higher risks of suicidal ideation and suicide attempts in patients with migraine.

Conclusion:

High migraine frequency has a correlation with high suicide risk in patients who experience an aura, but not in other patients with migraine.

This paper is cited in the neurochecklist

Migraine co-morbidities

Abstract link

The only consolation was this beautiful flower at Suicide Point. Shankar S on Flickr. https://www.flickr.com/photos/shankaronline/28484079831
Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s