Does diabetes reduce the risk of migraine?

Diabetes is associated with decreased migraine risk: a nationwide cohort study

Antonazzo IC, Riise T, Cortese M, et al.

Cephalalgia 2017 (Epub ahead of print).

Abstract

Background:

Results from studies on diabetes and migraine risk are conflicting, which may be due to methodological limitations. Prospective studies with long follow-up could increase our understanding of the relationship between the two diseases.

Method:

We performed a cohort study including the whole Norwegian population alive on 01.01.2004, using prescriptions registered in the Norwegian prescription database to identify individuals developing type 1 diabetes, type 2 diabetes and migraine during follow-up (10 years). We used Cox proportional hazards regression to estimate rate ratios with corresponding 95% confidence intervals for the effect of diabetes on migraine risk, adjusting for age, sex, and educational level.

Result:

We identified 7,883 type 1 diabetes patients and 93,600 type 2 patients during the study period. Type 1 diabetes was significantly associated with a subsequent decreased migraine risk during follow-up in the age- and sex-adjusted analyses (0.74; 0.61-0.89). Type 2 diabetes was also associated with a significantly lower migraine risk (0.89; 0.83-0.95). Further adjustment for educational level yielded similar results for both diabetes.

Conclusion:

Both type 1 and type 2 diabetes were significantly associated with a decreased risk of migraine. This suggests that diabetes or diabetes treatment may have a protective effect on the development of migraine.

Also see

Berge LI, Riise T, Fasmer OB, et al. Does diabetes have a protective effect on migraine? Epidemiology 2013; 24:129-134.

Both references are cited in the neurochecklist:

Migraine risk factors

Abstract link

By Reversing Your Diabetes Today – http://reversingyourdiabetestoday.com/https://pixabay.com/en/diabetes-blood-finger-glucose-777001/, CC0, Link
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