What has Diogenes got to do with frontotemporal dementia?

Diogenes syndrome in frontotemporal dementia

Finney CM, Mendez MF.

Am J Alzheimers Dis Other Demen 2017 (Epub ahead of print)

Abstract

Background:

Diogenes syndrome refers to the combination of extreme self-neglect and excessive collecting with clutter and squalor, which is often present in patients with dementia.

Methods:

Diogenes syndrome may be particularly common in behavioral variant frontotemporal dementia (bvFTD), and the investigation of these patients may help clarify the nature of this syndrome.

Results:

We describe 5 patients with bvFTD who exhibited a decline in self-care accompanied by hoarding behaviors. These patients, and a review of the literature, suggest a combination of frontal lobe disturbances: loss of insight or self-awareness with a failure to clean up or discard, a general compulsive drive, and an innate impulse to take environmental items. This impulse may be part of the environmental dependency syndrome in frontal disease, with specific involvement of a right frontolimbic-striatal system.

Conclusions:

Further investigation of the similarities and mechanisms of these symptoms in bvFTD could help in understanding Diogenes syndrome and lead to potential treatment options.

Frontotemporal dementia (FTD): behavioural variant

 

Abstract link

 

Diogenes the cynic. Now Idonoa on Flikr. https://www.flickr.com/photos/nowidonoa/15146904117
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