Is deep brain stimulation useful in super refractory status epilepticus?

Successful management of super-refractory status epilepticus with thalamic deep brain stimulation.

Lehtimäki K, Långsjö JW, Ollikainen J, et al.

Ann Neurol 2017; 81:142-146.


Super-refractory status epilepticus is a condition characterized by recurrence of status epilepticus despite use of deep general anesthesia, and it has high morbidity and mortality rates.

We report a case of a 17-year-old boy with a prolonged super-refractory status epilepticus that eventually resolved after commencing deep brain stimulation of the centromedian nucleus of the thalamus. Later attempt to reduce stimulation parameters resulted in immediate relapse of status epilepticus, suggesting a pivotal role of deep brain stimulation in the treatment response.

Deep brain stimulation may be a treatment option in super-refractory status epilepticus when other treatment options have failed

This abstract is now included in the neurochecklist

Super refractory status epilepticus

Abstract link

By Shamir R, Noecker A and McIntyre C – Shamir R, Noecker A and McIntyre C (2014) Deep Brain Stimulation. Front Young Minds. 2:12. doi: 10.3389/frym.2014.00012, CC BY 3.0, Link



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